Four analysis sessions of eight turns, with a standing instruction before the first turn and a closing instruction after the last. BC-1 and BC-2 use two Xenium sections of one breast cancer block; CRC-1 and CRC-2 a Visium HD and a Xenium section of one colorectal cancer patient. Regions were drawn through STAT's viewer.
Four runs per session: Run 1 with Claude Sonnet 4.6, Runs 2–4 with DeepSeek V4.1 Flash (seeds 10, 20, 30). A Claude Opus 5.5 rater rated each of the eight core turns 1–5 and the session as a whole 1–5.
| Condition | Run | Rating | |
|---|---|---|---|
| BC-1DCIS versus invasive breast cancer | |||
| STAT | Run 1 · Claude Sonnet 4.6 | turns 4.38 · session 4/5 | Replay → |
| STAT | Run 2 · DeepSeek V4.1 Flash · seed 10 | turns 4.75 · session 5/5 | Replay → |
| STAT | Run 3 · DeepSeek V4.1 Flash · seed 20 | turns 4.75 · session 5/5 | Replay → |
| STAT | Run 4 · DeepSeek V4.1 Flash · seed 30 | turns 4.88 · session 5/5 | Replay → |
| BC-2Immune exclusion and T-cell exhaustion | |||
| STAT | Run 1 · Claude Sonnet 4.6 | turns 4.88 · session 5/5 | Replay → |
| STAT | Run 2 · DeepSeek V4.1 Flash · seed 10 | turns 5.00 · session 5/5 | Replay → |
| STAT | Run 3 · DeepSeek V4.1 Flash · seed 20 | turns 4.88 · session 5/5 | Replay → |
| STAT | Run 4 · DeepSeek V4.1 Flash · seed 30 | turns 4.88 · session 5/5 | Replay → |
| CRC-1Goblet-cell changes near colorectal tumours | |||
| STAT | Run 1 · Claude Sonnet 4.6 | turns 4.75 · session 5/5 | Replay → |
| STAT | Run 2 · DeepSeek V4.1 Flash · seed 10 | turns 5.00 · session 5/5 | Replay → |
| STAT | Run 3 · DeepSeek V4.1 Flash · seed 20 | turns 5.00 · session 5/5 | Replay → |
| STAT | Run 4 · DeepSeek V4.1 Flash · seed 30 | turns 5.00 · session 5/5 | Replay → |
| CRC-2Tumour-associated macrophages | |||
| STAT | Run 1 · Claude Sonnet 4.6 | turns 5.00 · session 5/5 | Replay → |
| STAT | Run 2 · DeepSeek V4.1 Flash · seed 10 | turns 4.50 · session 4/5 | Replay → |
| STAT | Run 3 · DeepSeek V4.1 Flash · seed 20 | turns 5.00 · session 5/5 | Replay → |
| STAT | Run 4 · DeepSeek V4.1 Flash · seed 30 | turns 4.88 · session 5/5 | Replay → |